Central lines, PICC lines, and Midlinesoh my! Do you know the differences? Central Venous Catheters (CVCs) Placed in large vessel of neck or chest Long term therapy for those with poor peripheral Central Line Dressing Change, , Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called Olivia Linen Dress Dressing a Central Line Properly Maimonides Emergency Medicine Residency